From a ScienceDaily.com post on this:
Since external cues such as day-night lighting patterns and nutrition influence the circadian machinery, metabolites and their relationship to signaling proteins in cells seem to be acutely tied to circadian disruptions. This may help explain, Sassone-Corsi added, some of the primary physiological factors underlying obesity, high cholesterol and metabolic-based diseases like diabetes.
“This interplay has far-reaching implications for human illness and aging, and it is likely vital for proper metabolism,” he said. Study results appear this week in the early online edition of the Proceedings of the National Academy of Sciences.
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